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Study of the Bacterial Sensitivity to different Antibiotics which are isolated from patients with UTI using Kirby-Bauer Method

Journal of Biomedicine and Biochemistry, 2022, Volume 1, Issue 2, Pages 1-5

Abstract

Background: The Aim of the study was to determine the sensitivity of different types of bacteria to 30 different types of antibiotics by using Kirby-Bauer Method.
Methods: The study was conducted in December 2021 and January 2022, in Al-Samawah city. Where the study was conducted on 33 patients from both genders suffering from urinary tract infection, urine samples were collected using (First morning specimen), Where the chemical tests were carried out before the process of urine culturing by using petri dishes than bacterial species were isolated and their sensitivity to different antibiotics was determined.
Results: Staphylococcus aureus showed sensitivity to different antibiotics where the most effective antibiotic were Imipenem (100%). E. coli showed sensitivity to Amikacin, Imipenem and Meropenem by (100%). For Proteus mirabilis the most effective antibiotics were Amikacin, Cefotaxime, Ceftriaxone, Imipenem and Meropenem by (100%). For Streptococcus pyogenes the most effective antibiotics were Amikacin, Ciproflaxcine, Doxycycline, Imipenem, Meropenem, Norfloxacin, Rifampicin, Levofloxacin and Tetracycline (100%) and for Staphylococcus epidermidi were Cefepime, Norfloxacin, Nitrofurantoin, Piperacillin, Rifampicin, Gentamycin, Trimethoprim, Tobramycin and Levofloxacin (100%) and for Enterococcus faecalis were Cefotaxime, Ceftriaxone, Imipenem, Rifampicin and Meropenem (100%).
Conclusions: The current study shows Staphylococcus aureus and E. coli to be the most common pathogens in our study, with very high antibiotic sensitivities to Amikacin, Cefotaxime, Ceftriaxone, Imipenem and Meropenem and according to the C&S results.
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  1. CHO, Yong-Hyun. Introduction to urinary tract infections. Korean Journal of Urology, 2006, 47.6: 559-567.‏ doi: 10.4111/kju.2006.47.6.559
  2. DIELUBANZA, Elodi J.; SCHAEFFER, Anthony J. Urinary tract infections in women. Medical clinics, 2011, 95.1: 27-41.‏ doi: 10.1016/j.mcna.2010.08.023
  3. FOXMAN, Betsy, et al. Urinary tract infection: self-reported incidence and associated costs. Annals of epidemiology, 2000, 10.8: 509-515. ‏doi: 10.1016/S1047-2797(00)00072-7
  4. JOHNSON, James R.; STAMM, Walter E. Urinary tract infections in women: diagnosis and treatment. Annals of internal medicine, 1989, 111.11: 906-917.‏ doi: 10.7326/0003-4819-111-11-906
  5. ABOU HEIDAR, Nassib F., et al. Management of urinary tract infection in women: A practical approach for everyday practice. Urology annals, 2019, 11.4: 339.‏ doi: 10.4103/UA.UA_104_19
  6. PIETRUCHA‐DILANCHIAN1, Paula; HOOTON, Thomas M. Diagnosis, treatment, and prevention of urinary tract infection. Urinary Tract Infections: Molecular Pathogenesis and Clinical Management, 2017, 41-68. doi: 10.1128/9781555817404.ch3
  7. XIONG, Huaiyu, et al. A prognostic role for non-thyroidal illness syndrome in chronic renal failure: a systematic review and meta-analysis. International Journal of Surgery, 2019, 70: 44-52.‏ doi: 10.1016/j.ijsu.2019.08.019
  8. QUIGLEY, Raymond. Diagnosis of urinary tract infections in children. Current Opinion in Pediatrics, 2009, 21.2: 194-198.‏ doi: 10.1097/MOP.0b013e328326f702
  9. LI, Adela Jing; MARTINEZ-MORAL, Maria-Pilar; KANNAN, Kurunthachalam. Variability in urinary neonicotinoid concentrations in single-spot and first-morning void and its association with oxidative stress markers. Environment international, 2020, 135: 105415.‏ doi: 10.1016/j.envint.2019.105415
  10. BONNET, Maryline, et al. Bacterial culture through selective and non-selective conditions: the evolution of culture media in clinical microbiology. New microbes and new infections, 2020, 34: 100622.‏ doi: 10.1016/j.nmni.2019.100622
  11. HERBERT, Silvia, et al. Repair of global regulators in Staphylococcus aureus 8325 and comparative analysis with other clinical isolates. Infection and immunity, 2010, 78.6: 2877-2889.‏ doi:10.1128/IAI.00088-10
  12. DUAN, Lixia; LIU, Chenxi; WANG, Dan. The General Population’s Inappropriate Behaviors and Misunderstanding of Antibiotic Use in China: A Systematic Review and Meta-Analysis. Antibiotics, 2021, 10.5: 497.‏ doi:10.3390/antibiotics10050497
  13. PATSALOS, Philip N.; SPENCER, Edgar P.; BERRY, Dave J. Therapeutic drug monitoring of antiepileptic drugs in epilepsy: a 2018 update. Therapeutic drug monitoring, 2018, 40.5: 526-548.‏ doi: 10.1097/FTD.0000000000000546
  14. OLMOS‐ORTIZ, Andrea, et al. Placentas associated with female neonates from pregnancies complicated by urinary tract infections have higher cAMP content and cytokines expression than males. American Journal of Reproductive Immunology, 2021, 86.3: e13434. doi:10.1111/aji.13434‏
  15. HABIB, Sabeen. Highlights for management of a child with a urinary tract infection. International journal of pediatrics, 2012, 2012.‏ doi: 10.1155/2012/943653
  16. BAQUERO, Fernando; LEVIN, Bruce R. Proximate and ultimate causes of the bactericidal action of antibiotics. Nature Reviews Microbiology, 2021, 19.2: 123-132.‏ doi: 10.1038/s41579-020-00443-1

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