Main Subjects : Toxicology


Discharge Plan for Mothers of Children Undergoing Congenital Heart Surgery

Michael P Doyle; M. Anthony McKervey

Journal of Biomedicine and Biochemistry, 2022, Volume 1, Issue 1, Pages 17-26

Background: Congenital heart defect is the second cause of death in infancy and childhood and is the leading cause of childhood morbidity and mortality. Congenital heart surgery corrects a heart defect that a child is born with it.
 Aim: This study aimed at evaluating the effect of discharge plans for mothers and their children undergoing congenital heart surgery. setting: this study was conducted at the outpatient clinic of Cardio Vascular and Thoracic Academy Ain Shams University Hospitals. Sample: 70 mothers and their children undergoing congenital heart surgery were included in this study.
Tools of data collection: two different tools were used. First tool: consists of interviewing questionnaire to asssocio-demographic his characteristics of mothers and their children, knowledge, reported practices of mothers for their children undergoing congenital heart surgery, Second tool: Assessment of child health status.
 
Result: revealed that 81.4% of the studied mothers achieved poor knowledge scores in the pre-implementation phase, it improved to 92.9% of them achieved well in the post-implementation phase. Only 18.6% & 7.1% of them achieved average in both the pre-and post-implementation phase respectively and 91.4% of the study sample's total mothers’ practice was unsatisfactory in the pre-implementation phase, but 97.1% of them were satisfactory in the post-implementation phase.
Conclusion: there was a strong statistically significant correlation between the mother's total knowledge and total reported practices score on the post-test (P<0.00**).
Recommendation: Comprehensive, multidisciplinary discharge planning should design early and should include the mothers and children contain education regarding congenital heart surgery care.

Secondary Metabolism Compounds Study of Essential Oils for the Mentha spicata L. and Ocimum basilicum L.

Raghad Khalil Alarkwazi; Gasaq Reaihd Abdulreda; Ali Salam Ali

Journal of Biomedicine and Biochemistry, 2022, Volume 1, Issue 1, Pages 27-33

Background: The mint and basil plants (M. spicata L. and O. basilicum L.) of the labiate family were used in the study.
 
Methods: A qualitative chemical detection regarding several active chemicals in the leaves of M. spicata L. and O. basilicum L. was part of the investigation.
 
Results: The findings revealed that both species include flavonoids and glycosides, yet tannins and saponins were not found in the leaves extract of O. basilicum, and volatile oils were found in the alcoholic extract at a rate of 4.5% in the leaves of O. basilicum. Fourier transform infrared spectrometry (FT-IR) was used to detect six chemical active groups include (O-H, C=H, C=C, C=N, C-O, C-N). Our findings revealed the presence of alkaloid; the extraction yield for volatile oils in M. spicata species is 3%. As for the presence of nutrients in the type, the highest percentage of Calcium is in species O. basilicum.
 
Conclusions: The presence of effective chemical compounds in O. basilicum and M. spicata leaves indicates its importance as a source of useful drugs and the importance of chemical components in the pharmaceutical industries, as well as enhancing the importance of its use in folk medicine as a safe treatment for many diseases.